Background.This study is aimed at exploring a case of choroidal Langerhans cell histiocytosis (LCH) successfully treated with systemic corticosteroid and immunosuppressant.Case presentation.A 24-year-old man with known multisystem LCH developed loss of vision, ocular pain, conjunctival injection, panuveitis, and a ciliochoroidal mass.
After receiving an intravenous methylprednisolone pulse, oral high-dose corticosteroids, full Zip Jacket and methotrexate, the mass resolved quickly and completely without flare-ups during 6 months of follow-up.Conclusions.Intraocular involvement of LCH is rare and can present with or without a Toddler Wetsuit history of multisystemic disease.The diagnosis is challenging, and the standard treatment is not established.
Systemic anti-inflammatory and immunosuppressive therapy could be an effective treatment, as the LCH itself contains an essential element of inflammation and the symptoms may be mainly inflammatory.